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ADMEquant is outfitted with state-of-the-art instrumentation which supports method development/validation and sample analysis activities. Our instrumentation includes:

LC/MS/MS
Sciex API 3000 and 4000 systems with APCI and Turbo Ion Electrosprays interfaced with binary pumps, degassers, column ovens, LEAP HTS PAL autosamplers, with 4-channel eluate LC 4-valve systems, cool stacks, and Analyst 1.4 software.

HPLC Systems

  • HP1050 quaternary gradient system with multiple wavelength UV detector, solvent degasser, and autosampler with expanded sample tray
  • HP1090 ternary gradient system with UV detector and autosampler
  • Pumps

    • Agilent 1100 binary pump with solvent degasser
    • HP1050 quaternary gradient pump with solvent degasser
    • Thermo Separation Products CM4100 quaternary gradient pump with solvent degasser
    • LDC Analytical CM4100 ternary gradient pump
    • Spectra-Physics SP8810 isocratic pump
    • Perkin Elmer series micro pumps

    Detectors

    • LDC Analytical 3100X variable wavelength UV
    • Two LDC Analytical 3200 variable wavelength UV
    • LDC Analytical SM4000 variable wavelength UV
    • HP 1046A fluorescence
    • ABI 980 fluorescence
    • Waters 470 fluorescence
    • ESA Coulochem II 5200 electrochemical
    • Berthold LB506C-1 radioactivity
    • Two Radiomatic Flo-One\Beta radioactivity
    • Shimadzu RID-6A refractive index

    Autosamplers

    • HP 1050 with expanded sample tray
    • Shimadzu SIL-9A capable of pre-column derivatization
    • Shimadzu SIL-10A capable of pre-column derivatization

GC

  • HP 5890 Series II with two programmable cool on-column inlets, two electron-capture detectors, and two autosamplers
  • HP 5890 with NPD and FID detectors and an autosampler
  • HP 5890 with FPD and electron-capture detectors and an autosampler

Liquid Scintillation Counters

  • Beckman LS 6500 for beta emitting isotopes with automatic quench correction, optimized color and chemical quench, chemiluminescence correction, low-level mode for improved sensitivity, and two-phase monitor

Miscellaneous

  • Varian Series 634 UV/Vis Spectrophotometer
  • Coulomatic Karl Fischer titrimeter model 447
  • R.J. Harvey OX-700 automated biological oxidizer for carbon-14 and tritium in solid samples
  • Two R.J. Harvey manual biological material oxidizers for carbon-14 and tritium in solid samples
  • Spectrum 20-Cell Spectra/Por equilibrium dialyzer
  • Pickering post-column derivatization system
  • PE-Nelson chromatography data system interfaced to HPLCs and GCs through a Novell intranet with in-house custom reporting programs
  • Gel Permeation Chromatograph (GPC)
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