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Method Development
ADMEquant offers method development and validation of bioanalytical methods in a wide variety of biological matrices utilizing solid-phase extraction (SPE) and solvent extraction with LC/MS/MS, HPLC, and GC quantitation, as appropriate. When method development or modification is necessary, we will review information provided by you or from a literature search. A method will then be developed based on that information as well as on our extensive experience. All methods are validated to document the performance of the method in our laboratory before conducting sample analyses. Method validation is conducted under GLP regulations according to industry/FDA criteria, unless requested otherwise.

Validated Assays – Proprietary and Non-Proprietary Compounds
Clinafloxacin   HPLC
Cyclosporin A   LC/MS/MS
Desipramine   HPLC
Dicyclomine   HPLC
Digoxin   LC/MS/MS
Ethinyl Estradiol   LC/MS/MS
Ethotoin   HPLC
 
Assays Under Development Non-Proprietary Compounds
Albuterol   LC/MS/MS
Amlodipine   LC/MS/MS
Atorvastatin   LC/MS/MS
Clonidine   LC/MS/MS
Esomeprazole   LC/MS/MS
Ezetimibe   LC/MS/MS
Fentanyl   LC/MS/MS
Levofloxacin   LC/MS/MS
Loratadine   LC/MS/MS
Moxifloxacin   LC/MS/MS
Naltrexone   LC/MS/MS
Pravastatin   LC/MS/MS
Prednisone   LC/MS/MS
Ritonavir   LC/MS/MS
Mepivacaine   LC/MS/MS
Metoclopramide   HPLC
Metoprolol   HPLC
Naproxen   HPLC
Norethindrone   LC/MS/MS
Omeprazole   LC/MS/MS
Paclitaxel   LC/MS/MS
Rosuvastatin   LC/MS/MS
Simvastatin   LC/MS/MS
Sufentanil   LC/MS/MS
Vardenafil   LC/MS/MS
 
Assays Planned for Future Development Non-Proprietary Compounds
Celecoxib   LC/MS/MS
Clopidogrel   LC/MS/MS
Duloxetine   LC/MS/MS
Duloxetine   LC/MS/MS
Escitalopram   LC/MS/MS
Fexofenadine   LC/MS/MS
Fluticasone   LC/MS/MS
Fluvastatin   LC/MS/MS
Valproic Acid   HPLC
Valsartan   LC/MS/MS
Warfarin (Racemic R & S)   LC/MS/MS
Lansoprazole   LC/MS/MS
Lovastatin   LC/MS/MS
Montelukast   LC/MS/MS
Olanzapine   LC/MS/MS
Pantoprazole   LC/MS/MS
Quetiapine   LC/MS/MS
Quinapril/Quinaprilat   LC/MS/MS
Ramipril/Ramiprilat   LC/MS/MS
Risperidone   LC/MS/MS
Sertraline   LC/MS/MS
Topiramate   LC/MS/MS
Topotecan   LC/MS/MS
Zolpidem   LC/MS/MS

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