Through the Azopharma Product Development Group, ADMEquant provides comprehensive preclinical services to support your regulatory filings. Our team of researchers has been serving the life sciences industry for over 40 years. We are AALAC accredited, licensed and registered with the USDA and support both GLP and non-GLP studies. We maintain one of the largest Pharmacokinetic colonies available in the industry. Our facilities are designed to accommodate large test groups in various housing arrangements that can be easily modified to meet even the most rigid test requirements.

Services/Capabilities

• Pharmacokinetic and pharmacodynamic studies
• Blood/plasma concentration analysis
• Metabolism, excretion, absorption and distribution studies
• Acute, subchronic, chronic toxicology and carcinogenicity studies
• Characterization to determine severity and reversibility of adverse effects
• Dose response relationship development
• Assistance for clinic dose selection
• Inhalation toxicology

Dosing Routes

• Oral, buccal and sublingual administration
• Duodenal, colonic and rectal administration
• Subcutaneous and intramuscular administration
• Intravenous administration
• Transdermal and topical administration
• Inhalation administration

Animal Model Development

• Surgical implantation of medical devices to support cardiovascular and orthopedic research
• Specialty research models include vascular access ports, intestinal access ports and duodenal fistula models
• Rapid pharmacokinetic (PK) screens

Support Services

• Bioanalytical support
• Regulatory consulting
• Report writing
• IACUC review
• Research design